Home » Research Products » Recombinant Proteins » Mouse Interleukin-13

Mouse Interleukin-13

Product Code: 42450

 

Origin:

Recombinant

Cat. No.:

42450

Tag:

N-terminal 6xHis

Size:

0.1 mg

Source:

E.coli

Purity:

>95%

Other Names:

IL-13

Species:

Mouse

 

Description

Expressed in E.coli with total 135 AA. Mw: 15.2 kDa (calculated). 

N-terminal 6xHis-tag and TEV cleavage site, 25 extra AA (highlighted).

Recombinant antigen for research use or manufacturing only.

 

Introduction to the Molecule

Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. On B cells, it promotes cellular activation, immunoglobulin class switching to IgE, and the up‑regulation of CD23/Fc epsilon RII.  

 

Immunological Function

 

Amino Acid Sequence

MSYYHHHHHH DYDIPTTENL YFQGAPVPRS VSLPLTLKEL IEELSNITQD QTPLCNGSMV
WSVDLAAGGF CVALDSLTNI SNCNAIYRTQ RILHGLCNRK APTTVSSLPD TKIEVAHFIT
KLLSYTKQLF RHGPF

 

Endotoxin Level

<0.2 EU per 1 μg of the protein by the LAL method.

 

Formulation

Lyophilized at 1 mg/mL in NaCl 500mM, KCl 2.7mM, Na2HPO4 10mM, KH2PO4 1.8mM, pH 7.0.

 

Reconstitution

Add deionized water to prepare a working stock solution of approximately 1 mg/mL and let the

lyophilized pellet dissolves completely.

 

Storage

Store lyophilized protein at –20°C. Aliquot reconstituted protein and store at –80°C.  Avoid

repeated freezing /thawing cycles.

 

Quality Control Test

BCA to determine the quantity of the protein.

SDS PAGE to determine the purity of the protein.

 

SDS-PAGE Gel

 

 

 

 

Contact Us

 

Address:

 

5/F, Biotech Centre 2, No. 11 Science Park West Avenue, 

Hong Kong Science Park, Shatin, N.T., Hong Kong

Email: 

info@immunodiagnostics.com.hk      sales@immunodiagnostics.com.hk

Phone:

(+852) 3502 2780    

Fax:  

(+852)  3502 2781

 

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