Home » Research Products » Human fatty-acid binding protein 4 (A-FABP) ELISA

Human fatty-acid binding protein 4 (A-FABP) ELISA

Product Code: 31030
Cat. No.
Product
Assay range
Size
Price*
31030
Human FABP4 ELISA kit
0.20-50 ng/ml
96T/Kit
530.00 US$

 

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INTRODUCTION

 

FABP-4, also termed adipocyte fatty-acid binding protein (A-FABP) or AP2, has been shown to play a key role in obesity and metabolic syndrome. A-FABP knockout mice are substantially protected from insulin resistance, dyslipidemia, type 2 diabetes and fatty liver disease, despite of increased adipocity.
In clinical studies, increased circulating A-FABP levels are found in obese subjects and associated with non-alcoholic fatty liver disease, stroke, and carotid atherosclerosis.
 

 

TYPICAL STANDARD CURVE

 

The following standard curve is provided for demonstration only. A standard curve should be generated for each set of sample assay.

 

Human FABP4 standard curve (4-parameter)

 

ASSAY CHARACTERISTICS

 

A. Sensitivity:

The lowest level of FABP4 that can be detected by this assay is 0.20 ng/ml.

 

B. Specificity:

The antibodies used in this assay are specific to human FABP4 and do not cross-react with mouse and rat FABP4, and other cytokine or hormone molecules.

 

C. Precision:

Intra-assay Precision (Precision within an assay) C.V.< 4.1%.

Inter-assay Precision (Precision between assays) C.V.< 4.5%.

 

Publications Citing Our Products:

 

 Milner KL, et al. Hepatology. 2009; 49(6):1926-34. PMID: 19475694 
 Chow WS, et al. J Am Heart Assoc. 2013 Jan 15;2(1):e004176. PMID: 23525430 
 Ong, Kwok Leung, et al. J Clin Endocrinol Metab. 2012; 97(12):4701-8. PMID: 23144467 
 Liu, Mingya, et al. Clin Sci (Lond). 2013; 124(2):115-22. PMID: 23013043 
 Hao, Yaping, et al. J Clin Endocrinol Metab. 2014; 99(11):4321-7. PMID: 25127012 
 Hao, Yaping, et al. J Clin Endocrinol Metab. 2015; 100(5):2055-62. PMID: 25719934 
 Hu, Xiang, et al. Sci Rep. 2016 Jun 8;6:27762 PMID: 27270834
 Ni, Jie, et al. Cardiovasc Diabetol. 2013 Dec 21;12:176. PMID: 24359145 
 Bao, Yuqian, et al. PLoS One. 2011; 6(4):e19115. PMID: 21552513
 Zhou, Mi, et al. PLoS One. 2011; 6(10):e27032. PMID: 22046439 
 Hu, Xiang, et al. J Diabetes Investig. 2017; 8(4):582-589.  PMID: 27990767 
 Zhou, Mi, et al. Clin Sci (Lond). 2015 Oct;129(7):547-59.  PMID: 26186740

 

 

 

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