Home » Recombinant Mouse Fibroblast Growth Factor-21 (mFGF-21) without Tag

Recombinant Mouse Fibroblast Growth Factor-21 (mFGF-21) without Tag

Recombinant Mouse Fibroblast Growth Factor-21 (mFGF-21) without Tag
Product Code: 42189

Type:

Recombinant

Cat. No.:

42189

Tag:

None (his-tag removed)

Size:

100 µg

Source:

E.Coli

Purity:

>95%

Other names:

FGF21

Species:

Mouse

 

For bulk order or without FedEx acc, please contact us by email
Payable FedEx acc:

 

Introduction to the Molecule

FGF21 is a metabolic hormone mainly produced in liver. It regulates glucose and lipid metabolism through pleiotropic actions in multiple tissues, and protects against metabolic damages under various stresses.
In humans, high circulating FGF21 levels are found in obesity and multiple cardiometabolic disorders, including metabolic syndrome, type 2 diabetes, non-alcoholic fatty liver disease and coronary artery disease. Serum FGF21 is a potential biomarker for the early detection and risk prediction of these diseases.

 

Description

Total 184 AA Mw: 20kDa (calculated). N-terminal His-tag removed,

2 extra AA left (highlighted).

 

Amino Acid Sequence

GAAYPIPDSSPLLQFGGQVRQRYLYTDDDQDTEAHLEIREDGTVVGAAHRSPESLLELKALKPGVIQILG

VKASRFLCQQPDGALYGSPHFDPEACSFRELLLEDGYNVYQSEAHGLPLRLPQKDSPNQDATSWGPVR

FLPMPGLLHEPQDQAGFLPPEPPDVGSSDPLSMVEPLQGRSPSYAS

 

Formulation

Lyophilized in 1 mg/mL in PBS.

 

Endotoxin Level

<0.2 EU/ug.

 

Reconstitution

Add sterile deionized water to prepare a working stock solution of approximately 1 mg/mL

and let the lyophilized pellet dissolve completely.

 

Storage

Store lyophilized protein at –20°C. Aliquot reconstituted protein and store at –80°C.

Avoid repeated freezing /thawing cycles.

 

Quality Control Test

BCA to determine quantity of the protein.
SDS PAGE to determine purity of the protein.

 

Applications

Cell culture, animal studies, ELISA and Western blotting.

 

SDS-PAGE Gel                

 

Glucose Uptake Assay

 

 

 

Publications Citing Our Products:

 

So, W. Y., et al. Cell Death Dis. 2015; 6:e1707. 
Gong Q, Hu Z, Zhang F, et al. Hepatology. 2016; 64(2): 425-438.
So, Wing Yan, et al. Diabetes. 2013; 62(11):3751-9

 

 

 

 

Contact Us

 

Address:

 

5/F, Biotech Centre 2, No. 11 Science Park West Avenue,

Hong Kong Science Park, Shatin, N.T., Hong Kong

Email:

info@immunodiagnostics.com.hk      sales@immunodiagnostics.com.hk

Phone:

(+852) 3502 2780

Fax:

(+852)  3502 2781

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