Monoclonal Antibody Development
IMD has decades of experience in generating highly-specific mAbs using hybridoma technology, as evidenced by successful development of a large number of mAbs for research, clinical diagnosis and therapeutic applications. We know how to generate a mAb that is specific to the immunogens and that works for the intended application. Our service includes (1) design and production of peptide antigens; (2) immunization of BALB/c mice and cell fusion; (3) screening of positive clones using ELISA or Biacore system; (4) subcloning and expansion; (5) antibody isotyping and characterization; (6) cryopreservation of hybridoma cells; (7) bulk production and purification of mAbs with fermentation.
We have state of art facilities for mAbs production and characterization.
![Screenshot 2020-02-05 at 11.22.30 AM.png](https://static.wixstatic.com/media/0fbcf2_54d3ab9c1ac044caaa609d9dd6a278ee~mv2.png/v1/fill/w_748,h_178,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/Screenshot%202020-02-05%20at%2011_22_30%20AM.png)
Workflow of mAbs Production
![Screenshot 2020-02-05 at 11.23.10 AM.png](https://static.wixstatic.com/media/0fbcf2_0dac41418c0e4849a2df8473e3be5eda~mv2.png/v1/crop/x_0,y_44,w_1022,h_912/fill/w_60,h_53,al_c,q_85,usm_0.66_1.00_0.01,blur_2,enc_auto/Screenshot%202020-02-05%20at%2011_23_10%20AM.png)