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PmScl 75 (Human Exosome Component 9)

PmScl 75 (Human Exosome Component 9)

SKU: 41650

★ Download Datasheet PDF ★

 

 

Origin:

Recombinant

Cat. No.:

41650

Tag:

N-terminal 6xHis

Size:

0.1 mg

Source:

Spodoptera frugiperda Sf9

Purity:

>90%

Other Names:

EXOSC9, PmScl 75

Species:

Human

  • INTRODUCTION

    Exosome component 9 (EXOSC9 or PmScl-75) is the non-catalytic component of RNA exosome complex, which is involved in the processing and degradation of RNAs. PmScl-75 is essential in the binding and presentation of RNA for ribonucleolysis, and acts as a scaffold for the accessory proteins or complexes, associates with the catalytic subunits and facilitates their activities.

  • IMMUNOLOGICAL FUNCTION

    As an autoantigen, PmScl-75 binds with IgG-type human auto-antibodies.

  • AMINO ACID SEQUENCE

    MSYYHHHHHHDYDIPTTENLYFQGAKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN

  • APPLICATIONS

    Standard ELISA test, line/dot assay and microarray assay with positive/negative sera panels.

  • FORMULATION

    Liquid in storage buffer (50mM Tris, 300-500mM NaCl, 10% Glycerol, Protease inhibitor, pH8.0).

  • DESCRIPTION

    Expressed in insect Sf9 cells with a total of 480 AA.

    Mw: 53.8 KDa (calculated).

    N-terminal 6xHis-tag and TEV cleavage site, 25 extra AA (highlighted).

    Recombinant antigen for research use or manufacturing only.

     

  • STORAGE

    Store at –80°C. Avoid repeated freezing/thawing cycles.

  • QUALITY CONTROL TEST

    BCA to determine quantity of the protein.

    SDS PAGE to determine purity of the protein.

$374.00Price

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