FGF-basic (154aa), Human
Species: | Human |
Expression System: | E.coli |
MW: | 17-18 kDa (reducing) |
Accession: | P09038 |
Cat No. | UA040007 |
Endotoxin: | <1 EU/μg |
Purity: | >95% as determined by SDS-PAGE |
INTRODUCTION
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumor growth. Thus, bFGF is regarded as a target for cancers chemo preventive and therapeutic strategies.
Amino Acid Sequence
Ala135-Ser288
AAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKSPhysical Appearance:
Lyophilized powder
Buffer:
20 mM PB with 500 mM NaCl, pH 7.4
Reconstitution:
Reconstitute at less than 0.2 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
- 1 week, 2 to 8 °C under sterile conditions after reconstitution.
Note: Please avoid repeated freeze-thaw cycles