IL-1β, Mouse
Species: | Mouse |
Expression System: | E.coli |
MW: | 18 kDa (reducing) |
Accession: | P10749 |
Cat No. | UA040072 |
Endotoxin: | <1 EU/μg |
Purity: | >95% as determined by SDS-PAGE |
INTRODUCTION
Interleukin-1 beta (IL1 beta or IL1B) is a member of the interleukin 1 cytokine family. The interleukin-1 system (IL-1) is a prominent pro-inflammatory pathway responsible for the initiation and regulation of immune responses, but it has also received much attention for its pleiotropic neuromodulator effects under physiological and pathophysiological conditions.
Amino Acid Sequence
Val118-Ser269
VPIRQLHYRLRDEQQKSLVLSDPYELKALHLNGQNINQQVIFSMSFVQGEPSNDKIPVALGLKGKNLYLSCVMKDGTPTLQLESVDPKQYPKKKMEKRFVFNKIEVKSKVEFESAEFPNWYISTSQAEHKPVFLGNNSGQDIIDFTMESVSSPhysical Appearance:
Lyophilized powder
Buffer
20 mM Tris, 150 mM NaCl, pH 6.5
Reconstitution
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
- 1 week, 2 to 8 °C under sterile conditions after reconstitution.
Note: Please avoid repeated freeze-thaw cycles